The Tehran Metropolitan Region, as Iran’s most important economic and administrative center, holds a decisive position in the spatial organization of the national economy. This article examines the structure and interregional effects of spatial competitiveness in this region using a multi-regional input-output approach. Methodologically, the study is quantitative, applied, and exploratory. Its scope is the Tehran Metropolitan Region within to Iran’s national territory during the Iranian calendar year 1400 (March 2021-March 2022). Research data were compiled from national and regional accounts for 1400 and the national input-output table for 1395 (March 2016-March 2017), published by the Statistical Center of Iran, and used to estimate a seven-region input-output table. Economic relations were analyzed through two complementary methods: multiplier decomposition and spatial backward and forward linkage indices. On the one hand, multiplier decomposition shows that sectors such as chemicals, oil, agriculture, and construction have considerable internal capacity to form production clusters, and activities in food industries, chemicals, construction, and machinery can stimulate production in other regions. On the other hand, the spatial backward and forward linkage indices indicate that Tehran’s main role at the macro level is better understood in terms of demand generation, the concentration of advanced services, management, coordination, and the organization of economic networks. Therefore, rather than being an input-oriented industrial pole, Tehran functions as a metropolitan node of service-based, managerial, demand-driven, and network-based competitiveness within the national economy.