The aim of this study was to analyze barriers of Entrepreneurship Development in Enterprises of goods and services distribution network in Ilam province. A descriptive- survey method was used for this research. The statistical population of the study was experts and specialists familiar with the field of food distribution network of food distribution and Distribution Company that 30 experts and 3 food distribution companies were studied as a statistical sample. Instrument of data gathering was structured interview using Al Saati nine order professional questionnaires. The validity of questionnaire was considered by expert opinion of university professor and experts. The reliability of questionnaire assured by considering of Incompatibility of decision matrices due to judgment of each respondent. The analytic hierarchy process (AHP) and Expert Choice 11 and SPSS 23 software was used for data analysis. Findings showed that the most important barriers in Enterprises of goods and services distribution network were include as: infrastructural, economic, managerial, marketing, administrative-legal, human, and cultural Barriers, that among these factors, infrastructure factors were the most important barriers and cultural factors was the least important barriers in these Enterprises. Also, the results of the study of the following criteria for barriers to businesses in the distribution network of goods and services showed that Weakness of unions in the field of supervision, distribution and distribution of goods, the most deterrents are the businesses of the distribution network of goods and services in Ilam province.